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  • Innovation and Research
  • Kenneth P. Dietrich School of Arts and Sciences
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Heady math could resolve a breathy conundrum

Thackeray Hall exterior during daytime

Breathing happens without even thinking about it, but that doesn鈥檛 mean it鈥檚 simple.

Researchers have debated for years about how a group of brain cells called the preB枚tzinger complex governs breathing rhythms 鈥 and according to a study by two 51精品视频 researchers, explains many results that other scientists have found about how the process works.

Department of Mathematics Professor and Chair and Postdoctoral Researcher in the Kenneth P. Dietrich School of Arts and Sciences published the paper in April in the journal eLife.

To attempt to explain some apparently conflicting experimental results, the researchers started with a model of how specific charged atoms flow in a single brain cell, informed by data from experiments, then scaled up that model to the size of a whole network of cells. The model predicts that the flow of charged calcium atoms could explain patterns that researchers have seen in how brain cells synch up, providing a prediction that researchers can now test in their experiments.

The results, the duo writes, could 鈥渦nify a wide range of experimental findings鈥 on how brain cells get into rhythm and come to drive the rhythm of our breath.

Patrick Monahan