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What can vaccine proponents, clinicians and public health communicators learn from “anti-vaxxers?” A lot, according to new guidance for pro-vaccination social media events written by health scientists. 

The five-part guidelines, published today in the journal , arose from an analysis of a grassroots pro-vaccination campaign organized last year by popular physician and social media personality Zubin Damania, colloquially known as “.” Unexpectedly, more than three-quarters of the tweets associated with the event were opposing vaccination, researchers found.

“While at first it felt a little defeating that the event was co-opted to spread anti-vaccination messages, we learned some really constructive lessons,” said Beth Hoffman, a doctoral student at . Hoffman was the lead author with Jaime Sidani, assistant professor of medicine and core faculty member in the center, as the senior author on the paper. “I expect our guidelines will prove valuable now as health professionals work to address COVID-19 vaccine hesitancy and misinformation, as well as in the development of future health communication campaigns to promote vaccines.”

Following two separate instances in November 2019 and January 2020 where vaccination antagonists launched social media attacks, as well as harassed and personally threatened clinicians who had posted positively on social media about vaccination, ZDoggMD called on all health care professionals and vaccine advocates to speak up in support of vaccines using the hashtag on March 5, 2020. The event was supported by , a project of (PGP), a public health nonprofit responsible for some of the nation’s most successful health campaigns. Shots Heard was created in 2019 following a against pediatrics practice .

Hoffman and her team turned to to collect all publicly available tweets with the #DoctorsSpeakUp hashtag posted on March 5, 2020—a total of 106,275 tweets, of which 19,332 were original.

The team then analyzed a random sampling of original tweets, examining the type of account they came from (organization, health care professional, parent or both), whether they had pro- or anti-vaccine attitudes, and whether the tweet gave a personal narrative or made statements about research or science, or both.

The researchers found that 78.9% of the tweets were anti-vaccine, despite the event being organized as a pro-vaccination campaign. Only 5.4% came from “bots,” or automated accounts, which is lower than previous studies looking at bots that tweet about vaccines.

“The high level of anti-vaccine tweets and the low use of bots suggest this was a highly coordinated response by anti-vaccine antagonists,” said Sidani, assistant professor of . “This was not a coincidental convergence of people with anti-vaccine sentiment, nor was it an attack orchestrated by a few people or organizations deploying bots.”

After further examining the tactics the anti-vaccine movement used in co-opting the #DoctorsSpeakUp hashtag and event, Hoffman’s team developed guidelines for future pro-vaccine media events:

• Use best practices for risk communication, which include sharing personal narratives and citing scientific research.
• Leverage partnerships to create a broad coalition of vaccine advocates.
• Maximize inclusivity, for example, the #DoctorsSpeakUp hashtag didn’t represent the full complement of pro-vaccine advocates, which include nurses and parents, among others.
• Share a list of suggested tweets with stakeholders and potential participants prior to the event.
• Train event participants on responding to messages clearly and with compassion.

“Health professionals are highly trusted, but if they’re interacting only inside the four walls of an exam room, then they may not be providing their patients with health information when and where they need it,” said co-author pediatrician and chief executive officer of Kids Plus Pediatrics and founder of the Shots Heard Round the World project to aid health professionals targeted for their vaccine advocacy.

“True anti-vaccine activists are a very small group, but very effective communicators. About 20% of the general population can be described as vaccine hesitant—and many turn to social media with questions,” he said. “It’s critical that clinicians meet these people where they are, on social media, and learn how to use it effectively to counter anti-vaxxers and inoculate the public against misinformation.”

With a from the , the 51��Ʒ��Ƶ team is expanding upon this work to investigate COVID-19 vaccine misinformation by analyzing how people are connected on Twitter and what messages are being shared. The goal is to guide the creation and dissemination of effective educational messaging about the COVID-19 vaccines that can be shared through multiple platforms—social media, television, in-person discussions—to help people who may be hesitant to receive a vaccine make fact-based decisions. 

Additional authors on this research are Jason B. Colditz, Ariel Shensa, Riley Wolynn, Sanya Bathla Taneja and Elizabeth M. Felter, all of 51��Ʒ��Ƶ.

This research was supported by a grant R01CA225773. Technical infrastructure was supported through awards ACI-1548562 and 1445606 at the .